o:136 Sinteza, karakterizacija i potencijalna citotoksičnost O,O'-dialkil-(S,S)-etilendiamin-N,N'-DI-2-(4-metil)-pentanoati i odgovarajućih paladijum(II), platina(II) i platina (IV) kompleksa doktorska disertacija sr This works describes synthesis, characterization and potential cytotoxity of O,O'- -dialkyl-(S,S)-ethylenediamine-N,N'-di-2-(4-methyl)-pentanoic acid, [(S,S)-H4eddl]Cl2, as well as their corresponding palladium(II), platinum(II) and platinum(IV) complexes. Esters (S,S)-R2eddl·2HCl (R = ethyl, n-propyl, n-butyl and n-pentyl) were obtained by instillation of thionyl chloride in an appropriate absolute alcohol, and then refluxing with addition of (S,S)-ethylenediamine-N,N'-di-2-(4-methyl)-pentanoic acid. All of the esters were obtained as dihydrochlorides: (S,S)-Et2eddl·2HCl, (S,S)-Pr2eddl·2HCl, (S,S)-Bu2eddl·2HCl, (S,S)-Pe2eddl·2HCl. Esters were characterized by elemental analysis, IR and NMR spectroscopy, and in the case of (S,S)-Pr2eddl·2HCl the structure was confirmed by X-ray structural analysis. Прилози. Умножено за одбрану. ПРИРОДНО-МАТЕМАТИЧКИ ФАКУЛТЕТ, Универзитет у Крагујевцу., 2012, др хемијских наука. Извод ; Summary. Библиографија: листови 101-107. no D-2539 91552101 82 91552100 518247573 2013-01-25T15:27:11.053Z 45 no 46 mentor Jelena M., 1983- Vujić 2012 63 mentor Srećko R., 1954- Trifunović 2012 63 član komisije Goran N. Kaluđerović 2012 63 član komisije Tibor J., 1958- Sabo 2012 63 član komisije Nebojša, 1958- Arsenijević 2012 63 član komisije Biljana V., 1970- Petrović 2012 PDF/A (listova) 7313554 http://phaidrabg.bg.ac.rs/o:136 no yes 3 2013-01-25 70 Paladijum(II) kompleksi Platina(II) kompleksi Palatina(IV) kompleksi 54 54 1738 34A08 34A0803 2012